The Pamir Highway. It’s a name that vibrates strongly in the belly of anyone with a taste for adventure. The high desert of the Pamir invites expletives and superlatives. Like the Altiplano and the Tibetan plateau, this is a harsh and lonely place, inhabited by kind people. Its unforgiving landscape breathes tranquil spirituality. The M41 is the second-highest highway in the world, after the nearby Karakorum Highway. It crosses the whole Pamir region of Tajikistan, running from Osh to Khorog to Dushanbe. 
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Top 30 Things To Do In Tajikistan

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Tajikistan Activities

Dushanbe, One Day Excursion
CAD $138.78Per Person
Dushanbe to Osh on Pamir Highway
CAD $3,191.95Per Person
5 Day in Dushanbe
CAD $1,526.58Per Person
Fann Mountains, trekking, 10 days
CAD $1,373.93Per Person
Hisar Fortress, One-day tour
CAD $194.29Per Person
Dushanbe City Private Tour
CAD $83.27Per Person
Dushanbe to Iskandarkul lake
CAD $361.88Per Person